We introduce a pivot for exact selective inference with randomization. Not only does our pivot lead to exact inference in Gaussian regression models, but it is also available in closed form. We reduce the problem of exact selective inference to a bivariate truncated Gaussian distribution. By doing so, we give up some power that is achieved with approximate inference in Panigrahi and Taylor (2022). Yet we always produce narrower confidence intervals than a closely related data-splitting procedure. For popular instances of Gaussian regression, this price -- in terms of power -- in exchange for exact selective inference is demonstrated in simulated experiments and in an HIV drug resistance analysis.

Contrastive learning has been successfully used for retrieval of semantically aligned sentences, but it often requires large batch sizes or careful engineering to work well. In this paper, we instead propose a generative model for learning multilingual text embeddings which can be used to retrieve or score sentence pairs. Our model operates on parallel data in $N$ languages and, through an approximation we introduce, efficiently encourages source separation in this multilingual setting, separating semantic information that is shared between translations from stylistic or language-specific variation. We show careful large-scale comparisons between contrastive and generation-based approaches for learning multilingual text embeddings, a comparison that has not been done to the best of our knowledge despite the popularity of these approaches. We evaluate this method on a suite of tasks including semantic similarity, bitext mining, and cross-lingual question retrieval -- the last of which we introduce in this paper. Overall, our Variational Multilingual Source-Separation Transformer (VMSST) model outperforms both a strong contrastive and generative baseline on these tasks.

通过一系列联邦举措和命令，美国政府一直在努力确保美国在AI中的领导。这些广泛的战略文件影响了美国空军美国部（DAF）等组织。DAF-MIT AI加速器是DAF和MIT之间的一项计划，以弥合AI研究人员与DAF任务要求之间的差距。DAF-MIT AI加速器支持的几个项目正在开发公共挑战问题，这些问题解决了许多联邦AI研究的重点。这些挑战是通过公开可用的大型AI-Ready数据集，激励开源解决方案，并为可以激发进一步研究的双重使用技术创建需求信号，来针对优先事项。在本文中，我们描述了正在开发的这些公共挑战以及它们的应用如何促进科学进步。

我们提出Volux-GaN，一种生成框架，以合成3D感知面孔的令人信服的回忆。我们的主要贡献是一种体积的HDRI可发感方法，可以沿着每个3D光线沿着任何所需的HDR环境图累计累积Albedo，漫射和镜面照明贡献。此外，我们展示了使用多个鉴别器监督图像分解过程的重要性。特别是，我们提出了一种数据增强技术，其利用单个图像肖像结合的最近的进步来强制实施一致的几何形状，反照镜，漫射和镜面组分。与其他生成框架的多个实验和比较展示了我们的模型是如何向光电型可致力于的3D生成模型前进的一步。

大脑时代（BA）通过深度学习的估计已成为脑部健康的强大而可靠的生物标志物，但是神经网络的黑盒本质不容易让您深入了解大脑老龄化的特征。我们训练了重新网络模型来自524个个体的小横截面队列的T1结构MRI体积的BA回归。使用层的相关性传播（LRP）和深度逐步映射技术，我们分析了训练有素的模型，以确定网络脑老化的最相关结构，并在显着映射技术之间进行比较。我们显示了通过衰老过程与不同大脑区域相关性的归因变化。出现了对大脑区域的相关性归因的三方模式。一些区域与年龄相关性增加（例如，右颞回）；与年龄相关的相关性有所减少（例如，右四个心室）；和其他人在各个年龄段之间始终如一。我们还检查了大脑年龄间隙（BAG）对大脑体积中相关性分布的影响。希望这些发现将为正常的脑老化提供临床相关的区域轨迹，以及比较大脑衰老轨迹的基线。

我们提出了一种自我监督的预培训方法，用于学习手写和印刷历史文档转录的丰富视觉语言表示。监督我们预先调整我们预先培训的编码器表示两种语言的低资源文件转录后，（1）异构手写伊斯兰制稿件图像和（2）早期现代英语印刷文件，我们展现了有意义的认可改善从划痕培训的同一监督模型的准确性，只需30个线图像转录即可训练。我们屏蔽的语言模型式预培训策略，其中模型训练，以便能够识别从同一行中采样的患者的真正蒙面的视觉表示，鼓励学习强大的上下文化语言表示不变于抄写方式和打印噪声横跨文件。

Accurate determination of a small molecule candidate (ligand) binding pose in its target protein pocket is important for computer-aided drug discovery. Typical rigid-body docking methods ignore the pocket flexibility of protein, while the more accurate pose generation using molecular dynamics is hindered by slow protein dynamics. We develop a tiered tensor transform (3T) algorithm to rapidly generate diverse protein-ligand complex conformations for both pose and affinity estimation in drug screening, requiring neither machine learning training nor lengthy dynamics computation, while maintaining both coarse-grain-like coordinated protein dynamics and atomistic-level details of the complex pocket. The 3T conformation structures we generate are closer to experimental co-crystal structures than those generated by docking software, and more importantly achieve significantly higher accuracy in active ligand classification than traditional ensemble docking using hundreds of experimental protein conformations. 3T structure transformation is decoupled from the system physics, making future usage in other computational scientific domains possible.

Adversarial imitation learning (AIL) has become a popular alternative to supervised imitation learning that reduces the distribution shift suffered by the latter. However, AIL requires effective exploration during an online reinforcement learning phase. In this work, we show that the standard, naive approach to exploration can manifest as a suboptimal local maximum if a policy learned with AIL sufficiently matches the expert distribution without fully learning the desired task. This can be particularly catastrophic for manipulation tasks, where the difference between an expert and a non-expert state-action pair is often subtle. We present Learning from Guided Play (LfGP), a framework in which we leverage expert demonstrations of multiple exploratory, auxiliary tasks in addition to a main task. The addition of these auxiliary tasks forces the agent to explore states and actions that standard AIL may learn to ignore. Additionally, this particular formulation allows for the reusability of expert data between main tasks. Our experimental results in a challenging multitask robotic manipulation domain indicate that LfGP significantly outperforms both AIL and behaviour cloning, while also being more expert sample efficient than these baselines. To explain this performance gap, we provide further analysis of a toy problem that highlights the coupling between a local maximum and poor exploration, and also visualize the differences between the learned models from AIL and LfGP.

Many problems in machine learning involve bilevel optimization (BLO), including hyperparameter optimization, meta-learning, and dataset distillation. Bilevel problems consist of two nested sub-problems, called the outer and inner problems, respectively. In practice, often at least one of these sub-problems is overparameterized. In this case, there are many ways to choose among optima that achieve equivalent objective values. Inspired by recent studies of the implicit bias induced by optimization algorithms in single-level optimization, we investigate the implicit bias of gradient-based algorithms for bilevel optimization. We delineate two standard BLO methods -- cold-start and warm-start -- and show that the converged solution or long-run behavior depends to a large degree on these and other algorithmic choices, such as the hypergradient approximation. We also show that the inner solutions obtained by warm-start BLO can encode a surprising amount of information about the outer objective, even when the outer parameters are low-dimensional. We believe that implicit bias deserves as central a role in the study of bilevel optimization as it has attained in the study of single-level neural net optimization.

The Covid-19 pandemic induced a vast increase in adolescents diagnosed with eating disorders and hospitalized due to eating disorders. This immense growth stemmed partially from the stress of the pandemic but also from increased exposure to content that promotes eating disorders via social media, which, within the last decade, has become plagued by pro-eating disorder content. This study aimed to create a deep learning model capable of determining whether a given social media post promotes eating disorders based solely on image data. Tweets from hashtags that have been documented to promote eating disorders along with tweets from unrelated hashtags were collected. After prepossessing, these images were labeled as either pro-eating disorder or not based on which Twitter hashtag they were scraped from. Several deep-learning models were trained on the scraped dataset and were evaluated based on their accuracy, F1 score, precision, and recall. Ultimately, the vision transformer model was determined to be the most accurate, attaining an F1 score of 0.877 and an accuracy of 86.7% on the test set. The model, which was applied to unlabeled Twitter image data scraped from "#selfie", uncovered seasonal fluctuations in the relative abundance of pro-eating disorder content, which reached its peak in the summertime. These fluctuations correspond not only to the seasons, but also to stressors, such as the Covid-19 pandemic. Moreover, the Twitter image data indicated that the relative amount of pro-eating disorder content has been steadily rising over the last five years and is likely to continue increasing in the future.